Also known as “erythermalgia” and “Mitchell disease,” erythromelalgia (EM) is a chronic, recurring syndrome characterized by the triad of pain, erythema, and increased temperature of...
A history of pain, erythema, and increased temperature of the extremities, typically the feet
Symptoms are intermittent, often bilateral, and typically worse at night (3).
Symptoms occ...
Avoid triggers: high environmental temperatures, alcohol use, heavy exercise, tight stockings, and shoe...
Complete blood counts to monitor for myeloproliferative disease, which may develop 2 to 3 years after diagnosis of EM (5)
Screen for depression.
37151006 Erythromelalgia (disorder)
403390002 Primary erythromelalgia (disorder)
403391003 Secondary erythromelalgia (disorder)
Consider EM in the differential diagnosis for patients presenting with painful, warm, erythematous red feet or hands.
Unlike peripheral artery disease which may have similar symptoms an...
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