A systemic disorder in allogeneic hematopoietic stem cell transplant (HSCT) recipients caused by donor T cells recognizing host (recipient) antigens as foreign initiating an immune r...
GVHD can affect any organ.
Frequent sites include skin, liver and GI organs; skin is often first involved.
Additional sites include oral, ocular, pulmonary, and neuromuscular systems.
Sy...
aGVHD is graded from 0 (absent) to IV (very severe).
cGVHD is graded from 0 (mild) to 3 (severe) based on individual organ severity.
Nutritional status, including oral ...
DiMaggio E. Acute Graft-versus-Host Disease: Emerging Insights and Updates into Detection, Prevention, and Treatment. Pharmacotherapy. 2020 Aug;40(8):788-807. ...
D89.813 Graft-versus-host disease, unspecified
D89.810 Acute graft-versus-host disease
D89.811 Chronic graft-versus-host disease
D89.812 Acute on chronic graft-versus-host disease
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aGVHD and cGVHD are defined by clinical manifestations and have separate pathophysiologies. aGVHD occurs early after transplant (< 100 days).
Skin, GIT, and liver are the common site...
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