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Loin Pain/Hematuria Syndrome

Kantima Phisitkul, MD Reviewed 05/2023
 


BASICS

DESCRIPTION

  • A rare and poorly understood syndrome characterized by unexplained, chronic, severe, intermittent or persistent, unilateral or bilateral loin/flank pain with microscopic or gross hem...

DIAGNOSIS

HISTORY

  • Chronic flank pain (>6 months) typically described as burning or throbbing that is severe, unilateral or bilateral, persistent, or recurrent. The duration is variable and may persi...

TREATMENT

GENERAL MEASURES

  • Focused on pain control

  • Most recommendations are based on observational studies, small case series, and anecdotal reports.

  • A multidisciplinary approach partnering medical and m...

ONGOING CARE

DIET

No restrictions 

PATIENT EDUCATION

  • It is a chronic pain syndrome with medical and psychological aspects.

  • Nephrectomy should be considered as a last resort.

PROGNOSIS

  • 1/3 of patients have a...

REFERENCES

1
Taba Taba Vakili  S, Alam  T, Sollinger  H. Loin pain hematuria syndrome. Am J Kidney Dis.  2014;64(3):460–472. [View Abstract on OvidMedline] ...

ADDITIONAL READING

Dube  GK, Hamilton  SE, Ratner  LE, et al. Loin pain hematuria syndrome. Kidney Int.  2006;70(12):2152–2155. [View Abstract on OvidMedline] ...

CODES

ICD10

  • R10.9 Unspecified abdominal pain

  • R31.9 Hematuria, unspecified

  • R31.2 Other microscopic hematuria

  • R31.0 Gross hematuria

SNOMED

  • 86208007 Loin pain-hematuria syndrome (disorder)

CLINICAL PEARLS

  • Loin pain/hematuria syndrome is a controversial disease with uncertain cause and pathophysiology.

  • It’s likely a common presentation of different pathologic entities.

  • All standard labs an...

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