Sickle Cell Disease in Pregnancy

It is critical to identify signs and symptoms related to hemolysis, vaso-occlusive disease, or infection early to avoid rapid decompensation.

Threshold for hospitalization with close m...

Preconception counseling (1,3,5):

• Women with SCD should seek preconception care to confirm diagnosis and receive counseling on possible pregnancy complications secondary to SCD (1)[C].

• Offer...

Progesterone only and barrier methods recommended for contraception

Do not restart hydroxyurea until patient has finished breastfeeding.

Regular s...

Alayed N, Kezouh A, Oddy L, et al. Sickle cell disease and pregnancy outcomes: population-based study on 8.8 million births. J Perinat Med.  2014;42(...

O99.019 Anemia complicating pregnancy, unspecified trimester

D57.1 Sickle-cell disease without crisis

D57.3 Sickle-cell trait

27342004 Anemia of pregnancy (disorder)

127040003 Hereditary ...

Preconception counseling for women with SCD is important.

Once pregnant, patient will require close antepartum monitoring.

SCD is associated with increased maternal and fetal morbidity/m...