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Mesothelioma

Brandon A Wilkins, D.O. and Laura B Bishop, M.D. Reviewed 05/2023
 


BASICS

DESCRIPTION

  • Mesothelioma is a rare, aggressive malignancy of the mesothelial or serous tissues primarily found in the pleura (65–70%) or peritoneum (20–33%), tunica vaginalis (1–2%) or pericardi...

DIAGNOSIS

Most often presenting symptoms are nonspecific so a thorough exposure history supported by imaging is most helpful. 

HISTORY

  • Symptoms are usually nonspecific and occur when disease is advanced...

TREATMENT

GENERAL MEASURES

  • A multidisciplinary team is important in management and should include thoracic surgery, oncology, pathology, pulmonary, and radiology for patient-specific planning of manage...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Smoking cessation

  • Immunization for pneumococcal pneumonia and influenza

Patient Monitoring

Monitor for paraneoplastic phenomenon, including fever, thrombocytosis, ma...

REFERENCES

1
Bridda  A, Padoan  I, Mencarelli  R, et al. Peritoneal mesothelioma: a review. MedGenMed.  2007;9(2):32. [View Abstract on OvidMedline]
2
...

CODES

ICD10

  • C45.1 Mesothelioma of peritoneum

  • C45.2 Mesothelioma of pericardium

  • C45.0 Mesothelioma of pleura

  • C45 Mesothelioma

  • C45.9 Mesothelioma, unspecified

  • C45.7 Mesothelioma of other sites

SNOMED

  • 161635002 ...

CLINICAL PEARLS

  • Mesothelioma remains a rare but universally fatal disease in part due to long latency.

  • Multimodal treatment has decreased recurrence rates and has extended survival time.

  • Main risk facto...

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