Presentation with hyperleukocytosis depends on the type of leukemia.
Percent with hyperleukocytos...
Symptoms and signs of hyperleukocytosis relate to the organ involved. Clinical evidence of leukostasis is most apparent in the CNS, lungs, retina, and penis.
CNS
Headache
Confusion
Blurre...
The goal of treatment is to quickly make a correct diagnosis and implement definitive therapy while simultaneously identifying and addressing the potential complications of leukostasis secon...
Patients usually require treatment in a pediatric intensive care unit because they require rapid and continuous monitoring at presentation and during early phase of therapy due t...
Blum W, Porcu P. Therapeutic apheresis in hyperleukocytosis and hyperviscosity syndrome. Semin Thromb Hemost. 2007;33(4):350–354. [View Abstract on OvidInsights]
Cairo M, Coiff...
288.60 Leukocytosis, unspecified
204.00 Acute lymphoid leukemia, without mention of having achieved remission
205.10 Chronic myeloid leukemia, without mention of having achieved remission
205.0...
Q: Is there a linear relationship between the WBC count and the presence/severity of clinical disease and complications?
A: No. Clinically significant hyperleukocytosis usually occurs at WBC ≥200,0...
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