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Immunoglobulin A Nephropathy, Pediatric

Maha N. Haddad, MD and Lavjay Butani, MD, MACM Reviewed 10/2018
 


BASICS

DESCRIPTION

Primary immune complex–mediated glomerulonephritis 

EPIDEMIOLOGY

  • Most common chronic glomerulonephritis worldwide

  • Prevalence varies considerably across countries; more common in Caucasi...

DIAGNOSIS

HISTORY

  • Clinical presentation varies widely in constellation of signs and symptoms and also in severity.

  • Patients may be completely asymptomatic.

  • In children, the most common presentation is re...

TREATMENT

  • Weak evidence base and mostly derived from expert opinion

  • Varies based on severity of renal impairment, amount of proteinuria, and whether or not the course is rapidly progressive with associ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

IgA nephropathy may be a progressive disease. Patients should be monitored periodically for the following: 
  • Kidney function tests

  • Level of proteinuria

  • Blood pressure

  • ...

ADDITIONAL READING

  • Edström Halling S, Söderberg MP, Berg UB. Predictors of outcome in paediatric IgA nephropathy with regard to clinical and histopathological variables (Oxford classification). Nephro...

CODES

ICD9

  • 583.9 Nephritis and nephropathy, not specified as acute or chronic, with unspecified pathological lesion in kidney

  • 583.2 Nephritis and nephropathy, not specified as acute or chronic, with les...

FAQ

  • Q: Will my child ever outgrow IgA nephropathy?

  • A: No. The etiology and pathogenesis of IgA nephropathy remain uncertain. IgA nephropathy is a chronic condition, but sometimes it can go into spontan...

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