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Zika Virus

Roselyn Jan W. Clemente-Fuentes, MD, FAAFP, Bonnie Gillis, MD and Alexis C. Aust, MD Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Zika virus is a single-stranded RNA virus (family Flaviviridae).

  • Transmitted by Aedes spp. mosquitoes (especially Aedes aegypti), which also transmit dengue and chikungunya

  • Incubation ...

DIAGNOSIS

HISTORY

  • Travel history to endemic area or outbreak

  • Most infections are asymptomatic. 20% of patients infected with Zika virus develop symptoms.

  • Fever, myalgia, joint pain, conjunctivitis, retro...

TREATMENT

GENERAL MEASURES

  • Usually mild and self-limited infection. Treatment is supportive (1)[B].

  • Avoid aspirin and NSAIDs if dengue is suspected to decrease hemorrhage risk.

  • Persons with Zika virus in...

ONGOING CARE

  • Zika virus disease is a nationally notifiable disease; health care providers are encouraged to report suspected cases to state health departments.

  • Lab-confirmed cases should be reported to...

REFERENCES

1
Oduyebo T, Polen KD, Walke HT, et al. Update: interim guidance for health care providers caring for pregnant women with possible Zika virus exposure—United States (including U.S. Territori...

ADDITIONAL READING

  • Adebanjo T, Godfred-Cato S, Viens L, et al. Update: interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection—United St...

CODES

ICD10

A92.5 Zika virus disease 

ICD9

066.3 Other mosquito-borne fever 

SNOMED

3928002 Zika virus disease (disorder) 

CLINICAL PEARLS

  • Clinical illness is generally mild and self-limited; most infections are asymptomatic.

  • Dengue virus can be cocirculating, and the clinical presentation can be similar; test to distingui...

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