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Zika Virus

Laura B Bishop, M.D. Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Zika virus is a single-stranded RNA arbovirus (family Flaviviridae).

  • Transmitted by Aedes spp. mosquitoes (especially Aedes aegypti), which also transmit dengue and chikungunya

  • Incubat...

DIAGNOSIS

HISTORY

  • Screen for travel to or residence in an area with active Zika transmission

  • Most infections are asymptomatic. Only 20% of patients infected with Zika virus develop symptoms:

    • Fever, myalg...

TREATMENT

GENERAL MEASURES

  • Usually mild and self-limited infection. Treatment is supportive (1)[B].

  • Avoid aspirin and NSAIDs if dengue is suspected to decrease hemorrhage risk. Acetaminophen is recomme...

ONGOING CARE

  • Zika virus disease is a nationally notifiable disease; health care providers are encouraged to report suspected cases to state health departments.

  • Lab-confirmed cases should be reported to...

REFERENCES

1
Oduyebo  T, Polen  KD, Walke  HT, et al. Update: interim guidance for health care providers caring for pregnant women with possible Zika virus exposure—United State...

ADDITIONAL READING

  • Adebanjo  T, Godfred-Cato  S, Viens  L, et al. Update: interim guidance for the diagnosis, evaluation, and management of infants with possible congenital ...

CODES

ICD10

A92.5 Zika virus disease 

SNOMED

3928002 Zika virus disease (disorder) 

CLINICAL PEARLS

  • Clinical Zika virus illness is generally mild and self-limited; most infections (>80%) are asymptomatic.

  • Dengue virus can be cocirculating, and the clinical presentation can be simil...

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