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Cryptogenic Organizing Pneumonia

Daniel R. Matta, DFPHM, FAAFP, MD, Alexis Jibril, MPH, MD and Tobi L Lawson, MD Reviewed 05/2023
 


BASICS

DESCRIPTION

  • Cryptogenic organizing pneumonia (COP) is a subclassification of idiopathic interstitial pneumonia (1).

  • It is an inflammatory process of the distal airways and alveoli with diffuse i...

DIAGNOSIS

Consider COP and the differential diagnoses in patients presenting with: 
  • Flulike illness that lasts 4 weeks or longer

  • Presumed infectious pneumonia that does not respond to antibiotics.

  • Fatig...

TREATMENT

  • Treatments have not been studied in randomized trials. Regimens are based on practice guidelines, case series, and clinical judgment.

  • Mild stable disease: Minimal symptoms and normal or borde...

ONGOING CARE

Resolution after proper treatment 

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Frequent visits

  • ​​​​Counseling on compliance of steroid use at every visit

  • Monitor lung disease and side effects...

REFERENCES

1
Travis WD, Costabel U, Hansell DM, et al. An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the ...

ADDITIONAL READING

Kavakli K, Ocal N, Dogan D, et al. Is there any superiority among diagnostic methods in organizing pneumonia in terms of clinical features of the patients? Th...

CODES

ICD10

J84.116 Cryptogenic organizing pneumonia 

SNOMED

129458007 Bronchiolitis obliterans organizing pneumonia (disorder) 

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