Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) most commonly present as obsessive-compulsive disorder (OCD) and/or tic disorder dev...

PANDAS are a clinical diagnosis.

Diagnostic criteria (2)[C],(3)[B]

• Presence of OCD or tic disorder symptoms

• Age of onset between 3 years and puberty

• Abrupt onset of symptoms or dramatic...

Antibiotics indicated specifically for the treatment of acute GABHS infections (2)[C]

Symptomatic treatment of OCD/tics with cognitive-behavioral therapy or selective serotoni...

Primary care or pediatric infectious disease for recurrent episodes of GABHS infection

Pediatric psychiatry

Pediatric neurology

Children enrolled in clinical trials ...

Chiarello F, Spitoni S, Hollander E, et al. An expert opinion on PANDAS/PANS: highlights and controversies. Int J Psychiatry Clin Pract.  2017;21(2):91–98. [View Abstract on Ov...

B95.0 Streptococcus, group A, causing diseases classd elswhr

D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified

F95.9 Tic disorder, unspecified

F42 Obses...

Consider testing for acute GABHS infection in children with abrupt onset of OCD symptoms or tics.

Prophylactic antibiotics and/or immunomodulatory therapy to treat PANDAS is not recomme...