Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Bartter and Schwartz criteria for SIADH:

• Decreased osmolality (<275 mosm/kg) with inappropriately concentrated urine (>100 mosm/kg) and euvolemia

Signs and symptoms depend upon...

Treat underlying cause/remove the offending agent

Fluid restriction (usually <1,000 mL/day) is recommended.

Avoid isoto...

Careful continuous clinical and laboratory monitoring of hyponatremic state during the acute phase:

• Hourly urine output

• Urine Na, urine potassium,...

Treatment of the underlying cause is key. Review all medications for potential culprits.

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