A rare but serious obstetrical diagnosis associated with significant maternal and neonatal morbidity and mortality
Due to a fetal/placental defect in β-oxidation of fatty acids, toxic...
Prodromal symptoms of malaise followed by nausea and vomiting
Jaundice, pruritus, coagulopathy, encephalopathy, ascites
Dehydration (dry mucous membranes, poor skin turgor, delaye...
Prompt recognition has resulted in improved outcomes (2).
Continuous maternal and fetal monitoring
Emergent delivery of fetus
Consider cesarean section if remote from vaginal d...
Continue to follow liver panel, chemistries, renal function, coagulation panel, complete blood count postpartum. Abnormalities can peak as late as postpartum day ...
K76.0 Fatty (change of) liver, not elsewhere classified
O26.619 Liver and biliary tract disord in pregnancy, unsp trimester
O26.611 Liver and biliary tract disord in pregnancy, first trimeste...
AFLP should be considered with any elevation of transaminases after the 20th week of pregnancy and in women with new onset vomiting and abdominal pain in the 3rd trimester.
AFLP is an o...
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