Chikungunya Fever

Dongsheng Jiang, MS, MD and Joanna Jiang, MD Reviewed 05/2023

BASICS

Chikungunya is a potentially disabling and debilitating zoonotic disease.

DESCRIPTION

Chikungunya virus (CHIKV) is a single stranded RNA virus (genus Alphavirus; family Togaviridae)
Transmitted b...

DIAGNOSIS

HISTORY

Asymptomatic: 15%
Symptoms: The virus is mostly arthrogenic but it can also affect CNS.
- Fever: Abrupt onset 3 to 7 days after an infected mosquito bite
- Polyarthralgia: 2 to 5 days after ...

TREATMENT

GENERAL MEASURES

Most patients recover fully; joint pain may persist for months or years (2).

MEDICATION

No known antiviral agents effective in human infection

First Line

Avoid aspirin and NSA...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Chikungunya fever is reportable. Notify state health officials of all suspected infections.

PROGNOSIS

Usually non-life threatening
Atypical and severe cases can occ...

REFERENCES

Constant LEC, Rajsfus BF, Carneiro PH, et al. Overview on chikungunya virus infection: from epidemiology to state-of-the-art experimental models. Front Microbiol. 2021;12:744164. doi: 10.3...

ADDITIONAL READING

Webb E, Michelen M, Rigby I, et al. An evaluation of global Chikungunya clinical management guidelines: a systematic review. EClinicalMedicine. 2022;54:10...

CODES

ICD10

A92.0 Chikungunya virus disease

SNOMED

111864006 Chikungunya fever

CLINICAL PEARLS

Chikungunya is characterized by an abrupt onset of fever and is frequently accompanied by debilitating joint pain.
Obtain serologies and virology studies (RT-PCR) in the 1st week after ...

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