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Ebola Virus Disease

Jake Van Weezep, DO and Alexander R Kim, CAQSM, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

  • An enveloped, negative-stranded RNA virus with a characteristic filamentous structure (family Filoviridae)

  • A high mortality rate and high transmissibility makes Ebola virus one of the...

DIAGNOSIS

HISTORY

  • No pathognomonic clinical signs or symptoms

  • The majority of patients present with fever. Other common early symptoms include fatigue, arthralgias, myalgias, anorexia, and headache.

  • A di...

TREATMENT

GENERAL MEASURES

  • A few viral particles are sufficient to cause infection. Observe maximal infection control precautions.

  • The CDC recommends standard, contact, and droplet precautions for isola...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • EVD is reportable to the National Notifiable Diseases Surveillance System.

  • Although patients may experience rapid improvement, they remain viremic for at least 21 ...

REFERENCES

1
World Health Organization. Ebola virus disease. https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease/. Accessed November 20, 2023. Last updated April 20, 2023.
2
PREVAC Study...

ADDITIONAL READING

SEE ALSO

Therapeutics for Ebola virus disease. Geneva: World Health Organization; 2022.  

CODES

ICD10

A98.4 Ebola virus disease 

SNOMED

  • 37109004 Ebola virus disease

  • 424206003 Ebolavirus

  • 422448009 Reston ebolavirus

  • 423042009 Ivory Coast ebolavirus

  • 424116003 Sudan ebolavirus

CLINICAL PEARLS

  • Ebola virus is one of the most virulent known human pathogens. It typically presents as an acute febrile illness with an accompanying gastrointestinal syndrome resulting in massive flu...

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