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Ebola Virus Disease

Sandeep S. Jubbal, MD and Steven Hatch, MD, MSc Reviewed 06/2019
 


BASICS

DESCRIPTION

  • An enveloped, negative-stranded RNA virus with a characteristic filamentous structure (family Filoviridae)

  • A high mortality rate, combined with the absence of specific antiviral treat...

DIAGNOSIS

HISTORY

  • No pathognomonic clinical signs or symptoms

  • The majority of patients present with fever. Other common early symptoms include fatigue, arthralgias, myalgias, anorexia, and headache.

  • A di...

TREATMENT

GENERAL MEASURES

  • A few viral particles are sufficient to cause infection. Observe maximal infection control precautions.

  • The CDC recommends standard, contact, and droplet precautions for isola...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • EVD is reportable to the National Notifiable Diseases Surveillance System.

  • Although patients may experience rapid improvement, they remain viremic for at least 21 ...

REFERENCES

1
World Health Organization. Ebola virus disease. http://www.who.int/ebola/situation-reports/drc-2018/en/. Accessed October 29, 2018. http://www.who.int/ebola/situation-reports/drc-2018/en/....

ADDITIONAL READING

CODES

ICD10

A98.4 Ebola virus disease 

ICD9

078.89 Other specified diseases due to viruses 

SNOMED

  • 37109004 Ebola virus disease

  • 424206003 Ebolavirus

  • 422448009 Reston ebolavirus

  • 423042009 Ivory Coast ebolaviru...

CLINICAL PEARLS

  • Ebola virus is one of the most virulent known human pathogens. It typically presents as an acute febrile illness with an accompanying gastrointestinal syndrome resulting in massive flu...

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