40% of cases have abrupt onset. Clinical course often fluctuates.
Presentation can range from no symptoms to vague, nonspecific symptoms (right upper quadrant pain, nausea, jaundice, p...
Symptomatic therapy (antiemetics)
Hepatitis A and B vaccines
Treatment generally indicated if (3)[C]:
AST >10 × ULN
AST >5 × ULN with serum γ-globulin >2 × UL...
Follow AST, ALT, total bilirubin, and IgG every 1 to 3 months during treatment.
Treat until levels normalize and liver histology is no longer inflammatory.
AIH is a t-cell mediated autoimmune response in genetically predisposed individuals. AIH disproportionately affects women.
Presentation of AIH ranges broadly from asymptomatic elevation...
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