40% of cases have abrupt onset. Clinical course often fluctuates.
Presentation can range from no symptoms to vague, nonspecific symptoms (right upper quadrant pain, nausea, jaundice, p...
Symptomatic therapy (antiemetics)
Hepatitis A and B vaccines
Treatment generally indicated if (3)[C]:
AST >10 × ULN
AST >5 × ULN with serum γ-globulin >2 × U...
Follow AST, ALT, total bilirubin, and IgG every 1 to 3 months during treatment.
Treat until levels normalize and liver histology is no longer inflammatory.
Continue treatment for 3 to 6 months (even if rapid clinical and laboratory improvement) to allow for histologic resolution.
ALP: AST (or ALT) ratio of <1.5 suggests AIH.
Sign up for a 10-day FREE Trial now and receive full access to all content.