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Oral Allergy Syndrome

Whitney A. Dunlap, MS, MD Reviewed 05/2023
 


BASICS

DESCRIPTION

  • Allergic symptoms confined primarily to the oropharyngeal cavity caused by ingestion of raw plant foods is known as oral allergy syndrome (OAS).

  • OAS: where sensitization to a plant-de...

DIAGNOSIS

HISTORY

  • Within 5 minutes of ingesting raw fruits, vegetables, legumes (eg, peanut, soy), or nuts, patients experience sensation of itching, tingling, or numbness of the mucosa of the mouth, l...

TREATMENT

GENERAL MEASURES

  • Avoidance of symptom-causing foods

  • For the majority of patients with fruit and vegetable-induced OAS, consumption of the food in a cooked form is safe and well tolerated.

  • Most ...

ONGOING CARE

PATIENT EDUCATION

  • The following conditions may increase the risk of anaphylaxis: (i) consumption of large amounts of the raw food on an empty stomach, (ii) consumption of the raw food duri...

REFERENCES

1
Pascal  M, Muñoz-Cano  R, Reina  Z, et al. Lipid transfer protein syndrome: clinical pattern, cofactor effect and profile of molecular sensitization to plant-foods ...

CODES

ICD10

Z91.018 Allergy to other foods 

SNOMED

  • 432807008 Pollen-food allergy

  • 419452009 Allergic reaction to food

  • 414285001 Food allergy

CLINICAL PEARLS

  • Screen for and manage underlying associated allergic conditions.

  • Consider prescription for epinephrine autoinjector for those patients:

    • Who have had systemic symptoms with previous expos...

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