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Zika Virus Infections in Children, Pediatric

Anna Sick-Samuels, MD, MPH, Jeanne S. Sheffield, MD and W. Christopher Golden, MD Reviewed 10/2018
 


BASICS

DESCRIPTION

  • Zika virus is a single-stranded RNA flavivirus discovered in 1947 in the Zika forest in Uganda.

  • It is transmitted via mosquitoes (including Aedes aegypti and Aedes albopictus), sexual...

DIAGNOSIS

HISTORY

  • Travel history, including travel to or residence within a Zika-endemic region

  • Sexual relations with a person who has traveled to or resides within a Zika-endemic region

  • Abnormal fetal s...

TREATMENT

GENERAL MEASURES

  • Acute Zika infection

    • Supportive care fluids, rest, symptomatic treatment (acetaminophen for fever, antihistamines for pruritus)

    • Avoid salicylates (Reye syndrome risk).

    • Use nonst...

ONGOING CARE

PROGNOSIS

Acute Zika infection: Expect full recovery without sequelae within days up to 1 week. Severe disease requiring hospitalization is uncommon. 

COMPLICATIONS

  • A proportion of women wit...

ADDITIONAL READING

  • Adebanjo T, Godfred-Cato S, Viens L, et al. Update: Interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection—United St...

CODES

ICD9

066.3 Other mosquito-borne fever 

ICD10

A92.5 Zika virus disease 

SNOMED

  • 3928002 Zika virus disease

  • 762725007 Congenital infection caused by Zika virus

FAQ

  • Q: Can infants of women with suspected or confirmed Zika virus breastfeed?

  • A: Yes. At this time, although there has been evidence of viral RNA in breast milk, there have been no documented cases of...

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