The causative agent in anaphylaxis remains unknown in up to 1/3 of cases.
Food is the most common causative agent (about 1/3 of known cases) in children.
Pharmacotherapeutic agents are the most c...
Diagnosis is made based on clinical symptoms:
Do not underestimate the potential severity of an allergic reaction in its early stages.
Symptoms may progress rapidly.
Suspicion of anaphylaxis re...
Prehospital:
Airway, breathing, and circulation (ABCs)
Remove trigger (i.e., stinger from insect).
Early administration of epinephrine intramuscular (IM) in the anterolateral thigh positively a...
Liberman DB, Teach SJ. Management of anaphylaxis in children. Pediatr Emerg Care. 2008;24(12):861–866.
Lieberman P. Epidemiology of anaphylaxis. Curr Opin Allergy Clin Immunol....
Epinephrine is the undisputed initial therapy for anaphylaxis, and its administration should never be delayed.
There are no specific tests to make the diagnosis of anaphylaxis, and eval...
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