Brugada Syndrome, Sports Medicine

Chau Bui, DO and Paul Meirick, MD Reviewed 04/2019

BASICS

DESCRIPTION

Channelopathies refer to a group of inherited arrhythmogenic diseases caused by mutations in genes encoding for ion channel proteins in cardiomyocytes that disrupt the balance of cur...

DIAGNOSIS

Brugada pattern is used to describe those with typical ECG features but no other clinical criteria.
Brugada type 1 is diagnosed on the basis of 4:
- Type 1 ST-segment elevation (coved type) in ...

TREATMENT

The mainstay of treatment in Brugada syndrome is implantable cardioverter defibrillator (ICD), although quinidine has shown promising data as a preventative pharmacotherapy.

MEDICATION

Adjunc...

ONGOING CARE

All patients with channelopathies should be followed regularly by a cardiologist. Education and restrictions regarding exercise are crucial to survival.

FOLLOW-UP RECOMMENDATIONS

Return-to...

REFERENCES

Brugada J, Brugada R, Brugada P. Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circulation. ...

ADDITIONAL READING

Priori SG, Wilde AA, Horie M, et al. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endo...

CLINICAL PEARLS

Brugada syndrome most often affects the cardiac sodium channel and is characterized by ECG findings of a pseudo–RBBB, ST-segment elevation in leads V₁ to V₃, and an increased risk of S...

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