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Acalculous Cholecystitis

Frank J. Domino, MD Reviewed 04/2024
 


BASICS

DESCRIPTION

Acalculous cholecystitis, also known as acute alithiasic cholecystitis (AAC), is an acute necroinflammatory disease of the gallbladder occurring in the absence of cholelithiasis (1)...

DIAGNOSIS

  • The diagnosis of AAC can be challenging and relies on accurate history, physical examination, laboratory, and imaging (1).

  • Early diagnosis improves outcomes (4).

  • Diagnosis for Functional Gal...

TREATMENT

MEDICATION

  • Early treatment is essential for patients with AAC due to the risk of gangrene and perforation (4).

  • Early empiric antibiotic therapy should be initiated to cover gram-negative bact...

ONGOING CARE

PROGNOSIS

  • Acalculous cholecystitis is associated with several complications and a high mortality rate.

  • If treatment is delayed, mortality rates may be as high as 75%.

  • Critically ill patients...

REFERENCES

1
Balmadrid B. Recent advances in management of acalculous cholecystitis. F1000Res. 2018;7:F1000 Faculty Rev-1660. doi: 10.12688/f1000research.14886.1.
2
Ryu  JK, Ryu  K...

ADDITIONAL READING

SEE ALSO

Markaki I, Konsoula A, Markaki L, et al. Acute acalculous cholecystitis due to infectious causes. World J Clin Cases. 2021;9(23):6674–6685. doi: 1...

CODES

ICD10

  • K81 Cholecystitis
  • K81.0 Acute cholecystitis
  • K81.1 Chronic cholecystitis
  • K81.2 Acute cholecystitis with chronic cholecystitis
  • K81.9 Cholecystitis

SNOMED

  • 19968009 Cholecystitis without calculus
  • 5392...

CLINICAL PEARLS

  • Acute acalculous cholecystitis is a progressive inflammatory disease of the gallbladder presenting mostly in hospitalized patients. It has high morbidity and mortality if not addressed...

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