Zoonotic disease caused by Leptospira interrogans, a spirochete bacteria
Spread via contact with infected water; outbreaks common during increased rainfall or during floods
Infection can result in four broad clinical manifestations:
Self-limiting influenza-like infection that resolves in 1 to 3 weeks
Weil disease with renal and/or hepatic injury
Although most cases are self-limited and there is no decrease in mortality with antimicrobial treatment, it is currently recommended to treat all cases with antibiotics (4)[C...
Continue to monitor for evidence of severe disease following resolution of febrile stage.
No indication for test of cure following treatment
Dunay S, Bass J, Stremick J. Leptospirosis: a global health burden in review. Emerg Med. 2016;6:336. [View Abstract on OvidMedline]
Hartskeerl RA, Collares-Pereira M, Ellis WA....
A27.8 Other forms of leptospirosis
A27.89 Other forms of leptospirosis
A27.0 Leptospirosis icterohemorrhagica
A27.81 Aseptic meningitis in leptospirosis
Consider leptospirosis in patients with fresh water exposure who develop fevers, conjunctival suffusion, and/or cough.
Although rapid tests are being developed, MAT remains the gold sta...
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