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Xanthelasma

Adriana Arocha, MD and Jimena G. Cervantes, MD Reviewed 06/2022
 


BASICS

The term xanthelasma palpebrarum (XP) refers to the xanthomas that occur on the eyelids. They are also commonly known as just xanthelasmas  (1). They are benign yellow papules or plaques locate...

DIAGNOSIS

HISTORY

  • Usually asymptomatic, but depending on size and location, XP could cause visual disturbances.

  • Causes aesthetic concern  

PHYSICAL EXAM

  • Symmetric yellow-orange initially polygonal to roun...

TREATMENT

  • Treatment is mainly cosmetic, as XP is benign in nature.

  • There is no gold standard for treatment. 

  • Treatment is chosen by the patient after in depth discussion with physician on risks and bene...

FOLLOW-UP RECOMMENDATIONS

May require interdisciplinary team to have a holistic evaluation and treatment due to possible associations including dietician, PCP, endocrinology, dermatology, ophthalmolog...

REFERENCES

1
Bergman, R. The pathogenesis and clinical significance of xanthelasma palpebrarum. JAAD. 1994;30:236–242.
2
Nair P, Singhal R. Xanthelasma palpebrarum—a brief review. Clin Cosmet Investig De...

CODES

CLINICAL PEARLS

  • Xanthelasma palpebrarum is the most common cutaneous xanthoma.

  • XP are benign lesions characterized by symmetric yellowish papules or plaques on medial periorbital area; usually the uppe...

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