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General Medicine

Grover Disease

Emily Ann Gorman, DO Reviewed 04/2024
 


BASICS

Benign skin condition also known as transient acantholytic dermatosis. It is characterized by pruritic skin rash in non-sun exposed areas caused by irritation of sweat glands. Treatment is with...

DIAGNOSIS

The diagnosis of Grover disease is a clinical diagnosis based on history and physical examination. Skin biopsy can be used to confirm a diagnosis and exclude alternative diagnoses. 

HISTORY

Pa...

TREATMENT

Grover disease generally resolves spontaneously. Primary treatment is with avoidance of triggers and use of good general skin hygiene. Medications, particularly topical corticosteroids (2)[...

ONGOING CARE

PATIENT EDUCATION

American Osteopathic College of Dermatology: https://www.aocd.org/page/GroversDisease 

PROGNOSIS

Grover disease generally resolves spontaneously. 

COMPLICATIONS

Can lead to p...

REFERENCES

1
Gantz M, Butler D, Goldberg M, et al. Atypical features and systemic associations in extensive cases of Grover disease: a systematic review. J Am Acad Dermatol. 2017;77(5):952–957. 
2
Bellin...

CODES

CLINICAL PEARLS

  • Benign pruritic skin condition that generally spontaneously resolves

  • Often misdiagnosed

  • Common among those that are bedridden or have excessive sweat production

  • Treatment is targeted at ...

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