Pediatric Acute Onset Neuropsychiatric Syndrome (PANS)/Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS)

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) most commonly present as obsessive-compulsive disorder (OCD) and/or tic disorder dev...

The diagnosis of PANDAS is a clinical diagnosis.

Diagnostic criteria ⁽¹⁾

• Sudden or worsening presence of OCD or tic disorder symptoms

• Age of onset between 3 years and puberty

• Abrupt onset...

Antibiotics indicated specifically for the treatment of acute GABHS infections

Symptomatic treatment of OCD/tics with cognitive-behavioral therapy and/or selective serotonin r...

Primary care or pediatric infectious disease for recurrent episodes of GABHS infection

Pediatric psychiatry

Pediatric neurology

Children enrolled in clinical trials ...

B95.0 Streptococcus, group A, causing diseases classd elswhr

D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified

F95.9 Tic disorder, unspecified

F42 Obses...

Consider testing for acute GABHS infection in children with abrupt onset of OCD symptoms or tics.

Consider a diagnosis of PANS for children presenting with PANDAS-like symptoms in whom ...