When tying suture knots, properly squaring successive throws is important. That is, each tie must be laid down perfectly parallel to the previous tie by reversing the loops in each successive throw. When tying rope, this is accomplished using the memory aide “left over right and twist, and then right over left and twist.” With instrument ties, this is accomplished by alternating sides as the suture is twisted around the needle driver. This procedure is important in preventing the creation of a granny knot, which tends to slip and is inherently weaker than a proper square knot. The first throw in the knotting sequence is often looped or twisted twice, producing the surgeon’s knot. When the desired number of throws is completed, the suture material is cut (if interrupted sutures are used) or the next suture may be placed (if running sutures are used). An absolute minimum of three throws are needed for knot security, but some sutures require more throws to remain tied. When in doubt, five throws will hold almost all sutures securely.