Four techniques are commonly employed for shave biopsy. A no. 15 scalpel blade held horizontally in the hand can provide good control of depth. The ease of the scalpel technique makes it a frequent choice of inexperienced physicians. Horizontal slicing with a flexed razor blade is a time-honored method for shave biopsy. This technique is used less frequently because of the potential for injury from the large, exposed cutting surface. Scissors (e.g., iris scissors) can be effectively used to remove elevated lesions. Scissors removal of flat lesions can be more difficult. Radiosurgical loop removal is effective, although novice practitioners tend to create deeper, “scoop” defects in the dermis beneath the lesion being removed.