Acute respiratory distress syndrome (25% solution only): To correct interstitial pulmonary edema (in combination with diuretics) and hypoproteinemia associated with acute respiratory distress syndrome.
Cirrhotic ascites, therapeutic large volume paracentesis (adjunctive agent): To maintain intravascular volume following removal of large-volume paracentesis in cirrhotic patients.
Hypovolemia: Plasma volume expansion and maintenance of intravascular volume in select patients for the treatment of hypovolemia (with or without shock). For replacement of volume deficit, 5% solution is generally preferred.
Neonatal hemolytic disease: Binds and detoxifies unconjugated bilirubin in severe hemolytic disease of the newborn during exchange transfusion.
Nephrosis (acute) (adjunctive agent): Treatment of edema in patients with acute nephrosis in combination with diuretics.
Ovarian hyperstimulation syndrome, treatment (25% solution only): As a plasma volume expander in fluid management for the treatment of severe ovarian hyperstimulation syndrome.
Plasma exchange, therapeutic: To avoid excessive hypoproteinemia, during certain types of exchange transfusion, or with the use of very large volumes or previously frozen or washed red cells.