Hemophilia A:
Alphanate: Treatment and prevention of bleeding in adult and pediatric patients with factor VIII deficiency due to hemophilia A (classical hemophilia).
Humate-P: Treatment and prevention of bleeding in adults with hemophilia A (classical hemophilia).
Wilate: Treatment and prevention of bleeding in adults and pediatric patients ≥12 years of age with hemophilia A (classical hemophilia).
von Willebrand disease:
Alphanate: Surgical and/or invasive procedures in adult and pediatric patients with von Willebrand disease when desmopressin is either ineffective or contraindicated
Limitations of use: Not indicated for patients with severe von Willebrand disease (type 3) undergoing major surgery.
Humate-P: Treatment of spontaneous or trauma-induced bleeding, as well as prevention of excessive bleeding during and after surgery in adult and pediatric patients with severe von Willebrand disease, including mild or moderate von Willebrand disease where use of desmopressin is known or suspected to be inadequate.
Wilate: On demand treatment and control of bleeding episodes, perioperative management of bleeding, and prophylaxis to reduce the frequency of bleeding episodes in adult and pediatric patients with von Willebrand disease.